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Atrial Fibrillation

Key considerations: Rapid AFib with hemodynamic instability, WPW with AFib, New AFib from PE, sepsis, or MI

Cannot miss

  • Rapid AFib with hemodynamic instability
  • WPW with AFib
  • New AFib from PE, sepsis, or MI

Likely diagnoses

  • Atrial fibrillation
  • Atrial flutter
  • Multifocal atrial tachycardia
  • Frequent PACs

Red flags

  • Hemodynamic instability
  • Rate >150 with symptoms
  • Chest pain
  • Acute heart failure

Workup

  • history: Palpitations, dyspnea, duration, prior episodes, anticoagulation; exam: Irregularly irregular pulse, signs of CHF; labs: TSH, BMP, CBC, magnesium, troponin if chest pain; BNP if CHF concern; imaging: CXR, echo (evaluate for structural heart disease, LA size); bedside: 12-lead ECG

Management

  • immediate: Unstable: synchronized cardioversion 100-200J; Stable with RVR: IV diltiazem 0.25mg/kg bolus or metoprolol 5mg IV; general: Rate control target <110 bpm at rest; Anticoagulation: CHA2DS2-VASc score — DOAC preferred over warfarin; Rhythm control if symptomatic despite rate control

Disposition

  • admit: New AFib with heart failure, unable to rate control, requiring cardioversion; discharge: Known AFib with controlled rate and on anticoagulation; consults: Cardiology for ablation consideration, new-onset with structural disease

Clinical pearls

  • Unstable = cardiovert, regardless of anticoagulation status or duration
  • New-onset AFib <48hr can be cardioverted without TEE; >48hr needs TEE or 3 weeks of anticoagulation first

Source and review

  • AHA/ACC AFib Guidelines 2023. Last reviewed: 2024-11-01