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Hypertensive Emergency

Key considerations: Aortic dissection, Hypertensive encephalopathy, Eclampsia

Cannot miss

  • Aortic dissection
  • Hypertensive encephalopathy
  • Eclampsia
  • Acute heart failure
  • Intracranial hemorrhage

Likely diagnoses

  • Hypertensive emergency (with end-organ damage)
  • Hypertensive urgency (without end-organ damage)
  • Pain/anxiety-driven hypertension

Red flags

  • AMS
  • Chest pain
  • Back pain (dissection)
  • Visual changes
  • Papilledema
  • Acute kidney injury
  • Pulmonary edema

Workup

  • history: Medications, compliance, symptoms of end-organ damage, cocaine/stimulant use; exam: Fundoscopic exam (flame hemorrhages, papilledema), neurologic exam, cardiac exam, bilateral BPs; labs: BMP (creatinine), troponin, CBC, urinalysis (proteinuria), coags; imaging: CXR (pulmonary edema, widened mediastinum); CT head if AMS or focal neuro deficits; CTA if dissection suspected; bedside: Continuous BP monitoring, ECG

Management

  • immediate: IV antihypertensives: nicardipine, labetalol, or clevidipine drip; Target: 25% reduction in MAP in first hour, then toward 160/100 over next 2-6 hours; Aortic dissection: target HR <60 and SBP <120 rapidly with esmolol + nicardipine; general: Do NOT drop BP too quickly (risk of watershed infarct); Identify and treat underlying cause; Transition to oral antihypertensives when stable

Disposition

  • admit: All hypertensive emergencies to ICU for IV drip and monitoring; discharge: Hypertensive urgency (no end-organ damage): adjust PO meds, follow-up in 24-72hr; consults: Cardiology if ACS/CHF, neurology if stroke, nephrology if AKI

Clinical pearls

  • Hypertensive emergency = elevated BP + acute end-organ damage. Without organ damage, it is urgency.
  • Do NOT use sublingual nifedipine — unpredictable rapid drops cause stroke
  • Aortic dissection: reduce HR FIRST with beta-blocker, then add vasodilator — vasodilator alone causes reflex tachycardia

Source and review

  • AHA/ACC Hypertension Guidelines 2017. Last reviewed: 2024-11-01