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Placental Abruption

Key considerations: Concealed abruption (no visible bleeding), DIC from massive abruption, Fetal distress and demise

Cannot miss

  • Concealed abruption (no visible bleeding)
  • DIC from massive abruption
  • Fetal distress and demise
  • Uterine rupture (distinguish from abruption)

Likely diagnoses

  • Traumatic abruption
  • Hypertensive abruption
  • Cocaine-related abruption
  • Idiopathic abruption

Red flags

  • Trauma in pregnancy (even minor)
  • Cocaine use
  • Hypertension
  • Board-like rigid uterus
  • Fetal heart rate abnormalities
  • Absent fetal movement

Workup

  • history: Trauma, cocaine use, hypertension, vaginal bleeding, pain, fetal movement, gestational age; exam: Uterine tenderness and tone (board-like rigidity), fetal heart tones, vaginal bleeding assessment; labs: CBC, coagulation studies (fibrinogen most sensitive early marker); Type and crossmatch, Kleihauer-Betke test, urine toxicology; imaging: External fetal monitoring (Category II/III tracing); Ultrasound (only 50% sensitive — negative does NOT rule out); bedside: Continuous fetal monitoring, serial fibrinogen levels

Management

  • immediate: Large bore IV access x2, continuous fetal monitoring; OB emergency consult immediately; Severe or fetal distress: immediate cesarean delivery; general: Mild with reassuring fetal status: expectant management, betamethasone if <34 weeks; DIC treatment: FFP, cryoprecipitate (target fibrinogen >200), platelets, MTP if massive hemorrhage; Rh-negative mothers: RhIg administration

Disposition

  • admit: All suspected abruptions — L&D with continuous monitoring; discharge: Never with suspected abruption; consults: OB/GYN emergently, anesthesia for OR readiness, neonatology if preterm

Clinical pearls

  • In pregnancy, normal fibrinogen is 400-600 mg/dL — a level of 250 indicates significant consumption and impending DIC
  • Ultrasound is only 50% sensitive for abruption — clinical diagnosis in the setting of vaginal bleeding, pain, and uterine tenderness
  • Concealed abruption (retroplacental clot without external bleeding) can be catastrophic — amount of visible bleeding does not correlate with severity

Source and review

  • ACOG Practice Bulletin Placental Abruption 2021. Last reviewed: 2024-11-01