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Spinal Cord Compression

Key considerations: Metastatic spinal cord compression, Epidural abscess, Cauda equina syndrome

Cannot miss

  • Metastatic spinal cord compression
  • Epidural abscess
  • Cauda equina syndrome

Likely diagnoses

  • Metastatic cord compression
  • Epidural abscess
  • Central disc herniation
  • Vertebral fracture with retropulsion

Red flags

  • Progressive weakness
  • Bowel/bladder dysfunction
  • Saddle anesthesia
  • Sensory level
  • Cancer history with new back pain
  • Fever with back pain and neuro deficit

Workup

  • history: Back pain, weakness, bowel/bladder function, cancer history, fever, IVDU; exam: Motor exam, sensory level, rectal tone, post-void residual, Babinski, clonus; labs: CBC, ESR/CRP, blood cultures (if abscess suspected); imaging: EMERGENT MRI of entire spine (contrast if abscess/tumor suspected); If MRI unavailable: CT myelogram; bedside: Post-void residual, neurologic assessment

Management

  • immediate: IV dexamethasone 10mg bolus (cord compression from tumor); Emergent MRI — do NOT delay; Neurosurgery consult for surgical decompression; general: Metastatic: dexamethasone + radiation ± surgery; Epidural abscess: surgical drainage + IV antibiotics 6-8 weeks; Surgery within 24-48 hours improves neurologic outcomes

Disposition

  • admit: All spinal cord compression — emergent neurosurgical evaluation; discharge: Never acutely; consults: Neurosurgery, radiation oncology, ID (if abscess)

Clinical pearls

  • Back pain + neuro deficit + cancer history = cord compression until proven otherwise
  • Epidural abscess: classic triad of fever, back pain, and neuro deficit — but only present in ~10-15%
  • Once complete paralysis >48hr, recovery is very unlikely — early diagnosis is critical

Source and review

  • AANS Spinal Cord Compression Guidelines 2020. Last reviewed: 2024-11-01