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Vertigo / Acute Vestibular Syndrome

Key considerations: Posterior circulation stroke (cerebellar/brainstem), Vertebral artery dissection, Cerebellar hemorrhage

Cannot miss

  • Posterior circulation stroke (cerebellar/brainstem)
  • Vertebral artery dissection
  • Cerebellar hemorrhage

Likely diagnoses

  • BPPV
  • Vestibular neuritis/labyrinthitis
  • Meniere disease
  • Vestibular migraine

Red flags

  • HINTS exam suggesting central cause
  • Acute onset with vascular risk factors
  • Inability to walk
  • Focal neurological deficits
  • Severe headache
  • Hearing loss (acute)

Workup

  • history: Episodic vs continuous; Triggered by position vs spontaneous; Duration of episodes; Hearing changes, tinnitus; Headache, neck pain; exam: HINTS exam (Head Impulse, Nystagmus, Test of Skew); Dix-Hallpike maneuver; Gait assessment; Cranial nerves; Cerebellar exam (finger-nose, heel-shin, rapid alternating); labs: Glucose; Consider CBC, BMP if systemic cause suspected; imaging: MRI with DWI if central cause suspected (CT misses 50% of posterior fossa strokes in first 24h); CTA if dissection suspected; bedside: HINTS exam (most important bedside test); Dix-Hallpike for BPPV

Management

  • immediate: Assess for central vs peripheral cause using HINTS; IV access if concern for stroke; Antiemetics: ondansetron 4mg IV; general: BPPV: Epley maneuver (no medications needed); Vestibular neuritis: steroids (prednisone), short course vestibular suppressants; Avoid long-term vestibular suppressants (delay compensation); specific: diagnosis: BPPV; steps: Epley maneuver (posterior canal); Discharge with home exercises; No vestibular suppressants needed; diagnosis: Vestibular Neuritis; steps: Short-term vestibular suppressants (meclizine 25mg, diazepam 2mg); Prednisone taper; Vestibular rehabilitation referral; diagnosis: Central Vertigo (Stroke); steps: Stroke protocol — CT/CTA/MRI; Neurology consult STAT; tPA/thrombectomy if applicable

Disposition

  • admit: Central vertigo/stroke; Unable to ambulate safely; Intractable vomiting with dehydration; discharge: BPPV after successful Epley; Vestibular neuritis with adequate PO intake and safe ambulation; consults: Neurology if central cause suspected; ENT for recurrent peripheral vertigo

Clinical pearls

  • HINTS exam is MORE sensitive than MRI in first 24h for detecting posterior circulation stroke
  • Central: no corrective saccade on head impulse, direction-changing nystagmus, skew deviation
  • Peripheral: positive head impulse (corrective saccade), unidirectional nystagmus, no skew
  • CT is INADEQUATE for posterior fossa — MRI with DWI is needed if central cause suspected

Source and review

  • Kattah et al., Stroke 2009 (HINTS); Newman-Toker et al., Neurol Clin 2015. Last reviewed: 2024-11-01