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Escitalopram

Major depressive disorder, Generalized anxiety disorder

Indications

  • Major depressive disorder
  • Generalized anxiety disorder

Adult dosing

  • standard: dose: 10; unit: mg; route: PO daily; interval: May increase to 20mg after 1 week; max 20mg; fixed: true

Contraindications

  • MAOI use within 14 days
  • Concurrent pimozide
  • QTc prolongation (dose-dependent)

Clinical pearls

  • Most selective SSRI — fewest drug-drug interactions
  • QTc prolongation risk at doses >20mg — FDA black box
  • Elderly: max 10mg daily
  • Generally well-tolerated — good first-choice SSRI

Source and review

  • FDA Label; APA Practice Guidelines. Last reviewed: 2024-11-01