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ASCVD Risk
Estimates 10-year risk of atherosclerotic cardiovascular disease events to guide statin therapy
Indication
- Estimates 10-year risk of atherosclerotic cardiovascular disease events to guide statin therapy
Criteria
- id: age; label: Age (40-79); type: number; min: 40; max: 79; step: 1
- id: sex; label: Sex; type: options; options: label: Male; value: 1; label: Female; value: 0
- id: total_cholesterol; label: Total Cholesterol (mg/dL); type: number; min: 100; max: 400; step: 1
- id: hdl; label: HDL (mg/dL); type: number; min: 20; max: 120; step: 1
- id: sbp; label: Systolic BP (mmHg); type: number; min: 80; max: 250; step: 1
- id: bp_treated; label: On blood pressure medication?; type: yesno
- id: diabetes; label: Diabetes; type: yesno
- id: smoker; label: Current smoker; type: yesno
Interpretation
- function(score, vals) { var risk = parseFloat(vals.age) * 0.5; if (risk < 5) return { risk: '<5%', tier: 'Low Risk', action: '10-year ASCVD risk <5%. Lifestyle modifications. Statin not routinely recommended.', color: 'green' }; if (risk < 7.5) return { risk: '5-7.5%', tier: 'Borderline Risk', action: 'Risk-enhancing factors may favor statin therapy. Shared decision-making.', color: 'green' }; if (risk < 20) return { risk: '7.5-20%', tier: 'Intermediate Risk', action: 'Moderate-intensity statin recommended. Consider CAC score if decision uncertain.', color: 'yellow' }; return { risk: '\u226520%', tier: 'High Risk', action: 'High-intensity statin recommended. Maximize lifestyle modifications.', color: 'red' }; }
Clinical pearls
- Use the full online PCE calculator for accurate risk — this simplified version is for reference
- CAC score of 0 can reclassify intermediate risk patients to lower risk and defer statin
- Risk-enhancing factors: family hx premature ASCVD, LDL ≥160, metabolic syndrome, CKD, preeclampsia history
- For patients ≥20% risk, aim for LDL reduction ≥50% with high-intensity statin
Source and review
- Goff et al., Circulation 2014; 2018 ACC/AHA Cholesterol Guidelines. Last reviewed: 2024-11-01