RotationRx · Drugs · Scores · Protocols · Diagnoses · Specialties

← Clinical Scores and Calculators

Calcium Correction

Correct total calcium for low albumin. Low albumin artificially lowers reported total calcium.

Indication

  • Correct total calcium for low albumin. Low albumin artificially lowers reported total calcium.

Criteria

  • id: ca; label: Total Calcium (mg/dL); type: number; placeholder: e.g. 7.8
  • id: albumin; label: Serum Albumin (g/dL); type: number; placeholder: e.g. 2.0

Clinical pearls

  • Ionized calcium is the physiologically active form — measure directly when available rather than correcting
  • Each 1 g/dL drop in albumin below 4.0 lowers total calcium by approximately 0.8 mg/dL
  • Malignancy and primary hyperparathyroidism account for ~90% of hypercalcemia cases
  • The correction formula is less reliable in critically ill patients — prefer a direct ionized calcium

Source and review

  • Payne RB et al. Br Med J 1973. Last reviewed: 2025-01-01