← Clinical Scores and Calculators
CKD-EPI eGFR
Estimate GFR for CKD staging and drug dosing. More accurate than Cockcroft-Gault, especially at higher GFR values.
Indication
- Estimate GFR for CKD staging and drug dosing. More accurate than Cockcroft-Gault, especially at higher GFR values.
Criteria
- id: cr; label: Serum Creatinine (mg/dL); type: number; placeholder: e.g. 1.2
- id: age; label: Age (years); type: number; placeholder: e.g. 55
- id: sex; label: Sex; type: options; options: value: male; label: Male; value: female; label: Female
Clinical pearls
- CKD-EPI is more accurate than Cockcroft-Gault at higher GFR values — use for CKD staging
- Two measurements more than 3 months apart are needed for a formal diagnosis of CKD
- Creatinine is affected by muscle mass — may overestimate GFR in cachectic or elderly patients and underestimate in muscular patients
- The 2021 equation removed the race coefficient to address health equity concerns
Source and review
- Inker LA et al. NEJM 2021. Last reviewed: 2025-01-01